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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T28493 | R-547 mesylate | RO-4584820 mesylate,RG-547 mesylate | |
R547 Mesylate is a potent ATP-competitive inhibitor of CDK1, CDK2, CDK4 with Ki value of 2 nM, 3 nM, 1 nM respectively. | |||
T6312 | R547 | Ro 4584820 | Apoptosis , GSK-3 , PKA , CDK |
R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1. |